There are several reasons for the aggravation of cough after the application of Ambroxol: 1. Ambroxol is a phlegmolytic agent that promotes the secretion of sputum, stimulates the airway and induces an increase in cough, and many necrotic and inflammatory cells in the sputum remain in the airway. 2. The patient’s own airway conditions are poor and the cilia are short and few, so they cannot transport the sputum to the throat and spit it out, so the stimulation persists and leads to the aggravation of cough. 3. When applying amiloride, the patient is weak and has insufficient prana, so his own energy is consumed a lot and he is unable to expel the sputum effectively, which leads to coughing. The clinical application of Ambroxol is best combined with back tapping and postural sputum removal to promote sputum removal and cough relief.