Patients with hypertension who have both high and low pressure are recommended to choose calcium antagonists, such as amlodipine besylate tablets, levamlodipine besylate tablets, nifedipine extended-release tablets and nifedipine controlled-release tablets, which are commonly used in young people who have both high and low pressure at the same time. If an oral antihypertensive drug is not effective in lowering blood pressure, it can be combined with other antihypertensive drugs, such as angiotensin converting enzyme inhibitors, clinically used like Lortin, temisartan tablets, valsartan tablets, etc. The majority of elderly patients are mainly high pressure high, low pressure low, pulse pressure difference is relatively large, caused by atherosclerosis, you can also choose calcium antagonists to treat, the lowering effect is better, because this type of antihypertensive drugs to lower the pressure is more stable, and last longer.