Can hypertensive patients take antihypertensive drugs at night? The answer is that it varies from person to person. The pattern of blood pressure fluctuation in normal people is as follows: blood pressure rises after waking up in the morning and reaches the first peak at 10 am. Then it drops and waits until 3-5 p.m. for a second blood pressure peak, but lower than the first peak. Blood pressure drops at night, especially after sleep. If traced, it shows a spoon curve, but for a significant proportion of hypertensive patients, this normal curve disappears, called non-spoon curve, and even some have significantly higher blood pressure during the day and significantly lower blood pressure at night, called deep spoon. Many clinical studies have found that this non-spoon shape is more pronounced in the elderly, especially in those over 75 years of age. There are short-acting, medium-acting and long-acting antihypertensive drugs. For hypertensive patients whose blood pressure rises mainly during the day, we should take antihypertensive drugs during the day. If we take antihypertensive drugs at night, it may cause a significant drop in blood pressure at night, leading to cardiovascular accidents. However, for those patients who are not non-spoon type, this is possible to take at night to better control blood pressure. So for different hypertensive people, due to their different blood pressure fluctuation patterns, they should be treated separately to take antihypertensive drugs.