Clinically, there are many criteria for fatty liver, so how can we accurately confirm the diagnosis of fatty liver? It is mainly divided into four steps: analysis of medical history, laboratory tests, ultrasound and CT tests, and liver biopsy tests to confirm the diagnosis of fatty liver. 1, analysis of medical history: fatty liver has no specific symptoms. About half of the patients can have no obvious conscious symptoms, and some patients have easy fatigue, reduced appetite, abdominal distension, discomfort or vague pain in the liver area, nausea, warmth, etc. Experts from Zhengzhou Zhongda Liver Hospital remind that patients with fatty liver may have a history of long-term alcohol consumption or a history of diabetes, obesity, malnutrition and toxic liver injury. Some patients may have palpable hepatomegaly and may have mild pressure pain. 2. Laboratory tests: There may be changes in plasma globulins, especially increased α1, α2 and β lipoproteins, and mildly increased or normal serum GGT, ALT and activity. However, these are non-specific changes. 3.B ultrasound and CT detection: Ultrasound examination of fatty liver shows microfine dense strong reflective light spots in liver parenchyma and diminished deep tissue rebound. Ultrasound has a 95% diagnostic rate for severe fatty liver. CT scan shows lower density of the liver than other organs (e.g., normal spleen, blood vessels) and is generally considered to be more accurate than ultrasound in confirming the diagnosis of fatty liver. 4.Liver biopsy test: Liver puncture biopsy cytology is the only way to confirm the diagnosis of fatty liver. At present, liver puncture is mostly performed under the guidance of ultrasound, and liver tissue biopsy is aspirated, which is far more accurate and safe than the blind liver puncture method in the past, especially for focal fatty liver or diffuse chronic fatty liver with normal liver island, which has unique superiority when it is difficult to differentiate liver cancer under ultrasound. Microscopic observation of the biopsy tissue can clarify the extent and type of fatty liver lesions and the presence of combined steatohepatitis and liver fibrosis. This is also valuable for the treatment and prognosis of patients. However, because it is an invasive test, it is difficult for patients to accept. It is difficult to be accepted by patients and is relatively difficult to popularize. Reminder: Although fatty liver can be cured, if it is not diagnosed and treated early, over time, it will also threaten liver health to the liver. Modern people should strengthen the prevention of fatty liver, keep their mouths shut, open their legs, and stay away from risk factors such as alcohol to protect their liver health.