When anti-angiogenic drugs cause a faster heart rate or myocardial ischemia, it can be relieved by slowing down the infusion rate. For patients with special physical conditions, if the infusion does not work by this method, the infusion can be suspended first. At the same time, it can be improved by applying drugs that nourish the heart muscle or ordinary drugs that lower the heart rate. Another side effect of the application of anti-angiogenic drugs is to cause bleeding, and in severe cases, even hemoptysis. For this case, the doctor will make a comprehensive assessment before use, and if bleeding occurs during use, the first step is to stop the drug and take measures to stop the bleeding to prevent more serious bleeding. The side effects of anti-angiogenic drugs are generally reversible and reversible, so patients rarely discontinue the drug because of toxic side effects.