Patient question: disease: lung nodules content: description of the disease (onset time, main symptoms, hospital, etc.): twenty days ago due to lower abdominal pain two months to check the abdominal CT, found the left lower lung 1 * 0.6 glass-like nodules, no respiratory symptoms, and then check the tumor markers negative. Previous treatment and effect: The nodule did not change after half a month of anti-inflammatory treatment. What kind of help do you want: Can tuberculosis be excluded? What should be the further examination and treatment now? Thank you for your reply: Glassy nodule (GGO) depends on whether it is a mixed glassy nodule or a pure glassy nodule. The possibility of lung cancer in mixed glassy nodule is high, reaching about 90%, and the possibility of combined invasive lung cancer is high, while in pure glassy nodule, the possibility of early lung cancer is high. The likelihood of tuberculosis in ground glass nodules is low, conventional anti-infective treatment is poor, and the positive rate of percutaneous pulmonary puncture is low. The most common findings of ground glass nodules are early invasive adenocarcinoma (LEPITIC), microinvasive adenocarcinoma (MIA), adenocarcinoma in situ (AIS), benign atypical hyperplasia (AAH), and interstitial pneumonia. Milled glass nodules larger than 8 mm have a high malignant percentage and surgery is recommended. Surgery can usually be performed in a minimally invasive manner and no chemotherapy is required for early stage patients. If the nodule is smaller than 8mm, surgery is recommended if it has obvious burr sign or shows mixed GGO; if the nodule is smaller than 8mm, it is recommended to actively follow up if there is no obvious malignant feature. If the lesion does not change, the follow-up can be continued until 3 years; during the follow-up, if the lesion becomes solid, or if the lesion becomes larger, it is recommended to remove it surgically as soon as possible.