Chronic colitis is a benign lesion that, after effective treatment, does not usually have an immediate impact on patient survival. Chronic colitis is a chronic digestive disorder characterized by persistent congestion and ulceration of the lining of the colon. Bacterial infections, inadequate blood supply to the colon, and non-specific immune responses are common causes of chronic inflammation of the colon. The general signs of chronic colitis include abdominal pressure, diarrhea, watery stools, and fecal bleeding. With effective treatment, it generally has no impact on the patient’s life expectancy. The current treatment of chronic colitis depends on the cause of the colitis. If the chronic colitis is caused by a sensitive bacterial infection, it is necessary to identify the specific type of pathogenic bacteria through culture analysis, and then antibacterial treatment with antibiotics, such as ciprofloxacin, roxithromycin, penicillin sodium, etc. In addition, other types of drugs can be used to relieve the adverse symptoms, such as scopolamine, prednisone, and montelukast. In the case of patients with non-infectious colitis, antibiotic medications are not required and pharmacological palliative treatment is the mainstay. In severe cases, surgery may be an option, including removal of part of the diseased tissue of the colon and small intestine. Patients with chronic colitis should strengthen their daily diet as well as life care measures, try to maintain regular habits, maintain a light diet and pay attention to food hygiene and safety to avoid aggravating the development of the disease.