Injection therapy for stress urinary incontinence and its progress

  Stress urinary incontinence (SUI) in women is a more common disorder in women, especially in middle-aged and older women, and seriously affects the lives and work of many women.  Stress urinary incontinence in women refers to a sudden increase in abdominal pressure (rather than the contraction pressure of the detrusor muscle or the tension pressure of the bladder wall on the urine mass) such as standing, coughing, laughing, etc., resulting in involuntary urine flow. Some of the more severe SUI patients often have urinary urgency and develop the habit of urinating several times (urinary frequency) due to the fear of urine leakage when abdominal pressure suddenly rises; during urodynamic examination, SUI shows better bladder compliance and generally no uninhibited contraction of the forceps, the functional urethral length of SUI is often shortened, the pressure wave of the internal urethral sphincter becomes flat or disappears, and the maximum urethral closing pressure is significantly reduced; ultrasound urethral On examination, poor proximal urethral closure, bladder neck, and proximal urethra downward shift can be found. When patients with stress incontinence present with uninhibited contractions of the forceps urinaryis, they have mixed urinary incontinence.  There are many treatment methods for SUI, and there are more than a hundred surgical methods. The traditional bladder neck suspension and its modified surgical methods achieve better results by suspending the bladder neck to change the angle of the bladder neck and urethra. However, it is more traumatic and some patients are not easily supported by the suspension, resulting in overkill and urinary retention, and does not correct the underlying sphincter dysfunction. Others are pelvic floor muscle exercise, electrical stimulation, biofeedback therapy, urethral slinging, periurethral injection therapy and artificial urethral sphincter. Among them, injection therapy is popular among doctors and patients for its simplicity, safety and minimally invasive nature.  Injection therapy for SUI involves injecting drugs or chemical agents or autologous tissues into the posterior urethra or the submucosa of the bladder neck orifice to narrow, elongate and reduce the urethral cavity in order to increase urethral resistance, lengthen the functional urethral length and serve the purpose of closing the urethral orifice and posterior urethra, thus effectively controlling urination and generally not causing significant urinary obstruction. This treatment is therefore more effective in patients with stress urinary incontinence due to sphincter dysfunction and reduced intraurethral pressure. Situation [ ; With the development of the times and the popularization and application of technology, the lumpectomy technique is bound to play an increasingly important role in the treatment of UPJO.