Due to the complex etiology of scrotal eczema and easy to recur, it is difficult to completely cure it clinically, but it can be improved with standardized treatment. The causes of scrotal eczema include genetic factors, allergies, emotional anxiety and tension, etc. It often manifests itself as swelling, itching and erosion of the scrotal skin, and is prone to recurrent attacks. The treatment of scrotal eczema includes topical medication and oral medication. Topical medication includes glycerite lotion, tacrolimus ointment, etc.; oral medication includes benadryl and dexamethasone. These drugs do not exist the absolute safest and most effective, you need to follow the doctor’s advice to choose the most suitable for their own drugs, adverse reactions recommend seeking medical advice, drug allergy is prohibited. Through standardized drug treatment, it can effectively control clinical symptoms, reduce the recurrence of the disease, and significantly improve the quality of life of patients, patients are advised to relax and actively cooperate with the doctor to receive treatment.