1.What is biological DC-CIK immunotherapy? Zou Shansi, Department of Hematology and Oncology, The First Affiliated Hospital of Henan College of Traditional Chinese Medicine DC-CIK biological immunotherapy is an emerging and significantly effective treatment model for chronic liver diseases and tumors, and is a new autoimmune treatment method. Simply put, it is a method to stimulate and enhance the body’s autoimmune function by using biotechnology and biological agents to culture and amplify immune cells collected from patients in vitro and then transfuse them back into the patient’s body, so as to achieve the purpose of anti-tumor, anti-virus and regulation of immune function. Biological immunotherapy is the fourth major treatment technology for liver disease and tumor after surgery, radiotherapy and chemotherapy. DC cells, also known as dendritic cells, are like “radar”, which can actively search and identify viruses and tumor cells, and transmit the information to immune cells to activate them to kill viruses and tumors. DC cells are like “radar”, which can actively search and identify viruses and tumor cells, and transmit the information to immune cells to activate them to kill viruses and tumors. The two types of immune cells cooperate with each other, and each has its own function, which can bring the clinical effect of 1+1>2. 2.What are the indications for biological DC-CIK immunotherapy? (1) A variety of solid tumors, including malignant melanoma, prostate cancer, kidney cancer, bladder cancer, ovarian cancer, colon cancer, rectal cancer, breast cancer, cervical cancer, lung cancer, laryngeal cancer, nasopharyngeal cancer, pancreatic cancer and other solid tumors to prevent recurrence after surgery; (2) It can also be used for multiple myeloma, B lymphoma and leukemia and other hematologic malignancies to prevent recurrence, and can also be used for further consolidation treatment of the above tumors. It can also be used for further consolidation treatment of the above tumors to prolong survival, improve quality of life and inhibit tumor deterioration. (3) chronic viral hepatitis (hepatitis B and C), improve the clinical efficacy of antiviral drugs, improve immune function, delay the progression of the disease, and reduce the occurrence of na cirrhosis and hepatocellular carcinoma; 3, what are the advantages of biological DC-CIK immunotherapy? (1) Surgery, chemotherapy and radiotherapy combined with tumor cell immunotherapy can precisely remove residual tumor cells, prevent recurrence and metastasis, and improve patients’ survival quality and time. (2) Rapidly recover the immune damage caused by surgery and improve the success rate of surgery; (3) Reduce the immunosuppressive effect of chemotherapy drugs; (4) Reduce the pain and improve the survival quality of patients. (5) The above therapies together with Chinese medicine can significantly improve the immune function and quality of life of patients and prevent tumor recurrence. 4.DC-CIK bioimmunotherapy combined with Chinese medicine can be used to treat lung cancer at local or even genetic level, which can be called microscopic treatment, while Chinese medicine can regulate the whole body from macroscopic level to achieve the auxiliary or even direct treatment of lung cancer. lung cancer. Through long-term clinical observation, the role of TCM in reducing toxicity and increasing efficiency, or even directly killing tumor cells, due to its unique therapeutic method and adjuvant to radiotherapy, is gaining more and more attention. Through clinical observation, we found that the combination of Chinese herbal medicine with radiotherapy and chemotherapy is not only beneficial to the smooth implementation of radiotherapy and chemotherapy, but also has certain effects of inhibiting tumor growth, preventing cancer cells from spreading and metastasizing, and even directly killing tumor cells, which has played an irreplaceable therapeutic effect in improving patients’ quality of life and reducing the toxic side effects of chemotherapy. DC-CIK bioimmunotherapy combined with TCM evidence-based treatment has achieved satisfactory results in increasing the effectiveness and reducing the toxicity of malignant tumor treatment.