(1) Moderate or severe hyperthyroidism with ineffective or poor long-term drug therapy. ② Relapse after stopping medication with a large thyroid gland. ③Nodular goiter with hyperthyroidism. ④Compression on surrounding organs or retrosternal goiter. ⑤Suspected coexistence with thyroid cancer. ⑥Poor results of medication in children with hyperthyroidism. ⑦Pregnancy with poor results of medication, surgery may be considered in the middle stage.