1. Is the goal of treatment of polycystic ovary syndrome based on the success of pregnancy? Most clinical patients with PCOS have an urgent need for fertility or are seen for this reason. However, the goal of treatment for PCOS should not be judged by the success of pregnancy. The solution to fertility problems is generally a short-term problem and the key is a comprehensive, scientific and rational assessment of the patient by the physician. When the OGTT test + IRT test is abnormal, we also often advise patients to avoid pregnancy in the short term, and suggest correcting hyperinsulinemia, or insulin refusal, or IGT status, especially after reasonable and effective weight loss, before pregnancy is appropriate. In clinical practice, we see a lot of PCOS treatment, lack of doctor’s all-round assessment, the vast majority just blindly artificial cycle or ovulation treatment, which may potentially lead to patients gradually progress to DM, or early DM, try to prevent the occurrence of DM, or effectively delay the occurrence of the period, should be reflected in the doctor’s assessment or treatment plan or face-to-face education. It is often breathless to see the multitude of blind treatments. 2. Fertility and polycystic ovary syndrome, polycystic ovary syndrome development and prognosis? If a patient with polycystic ovary syndrome is in an endocrine disorder and conceives successfully, an important protective period is achieved and the rhythm and maturity of the ovaries and gonadal axis are further improved. The anovulation or irregular follicular development and the external manifestations of polycystic ovary syndrome, such as menstrual disorders or amenorrhea, as well as hyperandrogenemia, are corrected with the October conception process, after which the rhythm of the ovaries is The rhythm of the ovaries is then established. However, if some women have abnormal glucose tolerance test (OGTT) and/or insulin release test (IRT), or even impaired glucose tolerance (IGT), or if they already meet the diagnosis of diabetes mellitus (DM), then further weight gain during pregnancy and maintenance or increase of postpartum weight in these women will lead to a high risk group for DM, or inevitable development of DM, or further progression of DM. further progression of DM. Whether one is predisposed to diabetes or is a potential candidate for diabetes, or is developing diabetes may be the most important consideration in the development and prognosis of polycystic ovary syndrome. It is known that the incidence of IGT in adult women with PCOS is about 31-35% (or even higher), while the incidence of type II DM is 7.5%-10%, and their probability of developing type II DM from IGT is 5-10 times higher than that of normal women, suggesting that women with PCOS are a high-risk group for IGT and DM. IGT is a necessary stage in the natural course of DM from normal glucose metabolism to DM, which can last for several years or more. Therefore, assessment of DM propensity and its likelihood should be an important indicator of the development and prognosis of PCOS. hypertension, obesity, and the possibility of endometrial cancer in patients with PCOS are also associated with hyperinsulinemia, IR, IGT, or DM, or are key underlying factors. Focusing solely on prompting pregnancy and pregnancy alone as an end in itself lacks a comprehensive and more in-depth judgment. A lot of blinding is often seen in IVF, in artificial cycles, in ovulation promotion treatments, etc. This blindness only addresses pregnancy or fertility issues. That is, it does not take into account ovarian resources, let alone weight and the risk and possibility of disease progression, or progression to DM. In some cases, although fertility is resolved, there is a heavy or lifelong cost. Premature onset of DM, or depletion of ovarian resources. In clinical work, it is often seen that the incidence of gestational diabetes is increasing, often encountering cases that are partly undiagnosed and partly obtained in high-level hospitals with limited treatment and suboptimal control. These populations become a high-risk or potential population for DM. The increasing weight is a heavy burden for the islets if they are blindly gaining weight during pregnancy, or in the postpartum time, and if they are blindly enhancing their nutrition. All over the world, the increasing number of diabetes cases, their numbers keep adding up, and the ranks of DM keep increasing, bringing increasing medical costs. In many foreign health economics evaluations, a drug, a disease, in treatment, in daily life habits, etc., are weighed against health economics indicators that reflect the progress of a society. The increased burden of health care costs on the population is not just a matter for individuals and or families, but is the responsibility of society as a whole. Treatment methods, a drug, or prevention of disease, treatment of disease, etc. should be considered in an integrated manner, and doctors need to have the knowledge, the ability to conduct such research, and the health economics factors to consider. In this way the doctor will have the function of educating the population about health, which in itself is the honor of the profession. A reasonable lifestyle, limiting excessive energy intake, scientifically and reasonably evaluating the state of health, and clearly understanding the potential for disease development are called “Shang Gong” in Chinese medicine, which is a very high requirement and a general professional need. In clinical practice, we often see some pregnancy combined with hypertension, or acute fatty liver, or some pregnancy combined diseases. It often makes people think deeply about these diseases and daily life, and the communication between the doctor and the patient, the comprehensive and holistic judgment of the doctor, the scientific research skills possessed, etc., which often affect the health outcome. The doctor, not only coping with the disease, but more importantly, studying the disease and all the factors related to the disease. 3. To further improve the depth of understanding of polycystic ovary syndrome? I am afraid that it is a long-term process to further improve the understanding of PCOS, but of course, more research is needed. However, the superficiality of the clinical knowledge of many doctors about the complexity of PCOS directly leads to the inefficiency, blindness and arbitrariness of the treatment. Increasing the depth of knowledge of the disease among all physicians is of great importance for the scientific diagnosis and treatment of the large base of PCOS population.