Cough is a very annoying symptom, and some people do not get better with repeated infusions. However, many coughs are not caused by infection and repeated infusions and antibiotics are not always effective. If the cough is prolonged, a chest radiograph is needed to rule out tuberculosis, bronchiectasis, lung masses, atelectasis, lung infections, etc. If the chest X-ray is normal, or if you only see an increase in lung texture, you should first rule out nasopharyngeal problems, such as nasal congestion, runny nose, especially nasal mucus flowing backwards, and the need to clear the throat frequently, and if necessary, go to an otorhinolaryngologist. Next, we should rule out any gastroesophageal reflux. If there is no acid reflux, belching, burning sensation behind the sternum, if there is, anti-reflux treatment can be used. If there is no such condition, then there is a possibility of post-infectious cough, eosinophilic bronchitis, allergic cough, cough variant asthma, etc. A bronchial provocation test is recommended, and if cough variant asthma is diagnosed, it is treated as asthma. If cough variant asthma is ruled out, sputum and blood tests can be done in hospitals where available. A combination of anti-allergic and cough medicine, such as Asmac, or Chinese medicine such as Yinhuang Qinglung capsule, or Shunerin can be added. If there is no improvement, a chest CT is recommended to rule out rare causes. In conclusion, a cough that is not cured for a long time is not only a tracheal and pulmonary disease, but requires a comprehensive treatment with multiple considerations.