Tumor is still a persistent enemy of mankind. Its treatment is based on the principle of “comprehensive treatment with surgery as the mainstay”. The comprehensive treatment includes chemotherapy, radiotherapy, bio-immunotherapy, and Chinese medicine treatment. Surgery only minimizes the tumor load and achieves the radical cure of tumor as far as possible, but the so-called radical cure is only relative, absolute cure does not exist. Therefore, after surgery, some tumor cells or tissues will be left behind to a greater or lesser extent, and these tumor remnants can resurface and cause the tumor to come back. Therefore, most patients need comprehensive treatment after surgery. It is an indispensable supplement to surgical treatment, through which we can better control the tumor to prolong the patient’s life. With the continuous development of medicine, there are more and more elements of combination therapy. Chemotherapy by thermal perfusion (CHPP) is one of the new recruits in combination therapy. spratl first proposed continuous peritoneal chemotherapy by thermal perfusion in 1980, and later Japan performed CHPP after surgery for gastric cancer that broke through the whole layer and conducted a systematic randomized group study, which came to a convincing and positive conclusion: the concentration of drugs in the peritoneal tissue during CHPP is much higher than the plasma concentration, even up to 1000 times, and moreover Due to the absorption in the peritoneal cavity, the drug concentration in the portal system is also up to 10 times higher than that in the peripheral blood, which is good for the treatment of liver and pancreatic cancers.