Embolism is a clinical condition in which the teeth grow in the shape of an embolism due to certain diseases. Embolism is one of the clinical manifestations of pediatric dyschromia. Dyschromatosis is also known as pigmentary incontinence, Bloch-Sulzberger syndrome, Bloch-Siemens syndrome, and dermal degenerative melanosis. It is a rare complex genetic syndrome with characteristic skin changes that can be accompanied by malformations and abnormalities of the eyes, bones and central nervous system. Premarital physical examination plays a positive role in the prevention of birth defects, and the size of the role depends on the examination items and contents, mainly including serological examination (such as hepatitis B virus, syphilis spirochetes, HIV), reproductive system examination (such as screening for cervical inflammation), general physical examination (such as blood pressure, electrocardiogram) and asking about family history of the disease, personal past medical history and so on, and make good counseling for hereditary diseases. Pregnant women avoid hazardous factors as much as possible, including staying away from smoke, alcohol, drugs, radiation, pesticides, noise, volatile harmful gases, and toxic and harmful heavy metals. Systematic screening for birth defects is needed in the course of prenatal care during pregnancy, including regular ultrasonography, serologic screening, etc., and chromosomal testing when necessary. Once abnormal results appear, it is necessary to clarify whether to terminate the pregnancy; the safety of the fetus in the uterus; whether there are sequelae after birth, whether it is treatable, and what is the prognosis and so on. Practical diagnostic and therapeutic measures should be taken. Differential diagnosis with epidermolysis bullosa, childhood herpetic pemphigoid, depigmented pigmentary incontinence, and Franceschetti-Jadasson syndrome is needed.