To date, the exact etiology of Parkinson’s disease is not well understood, and therefore preventive measures lack precise targeting. However, many studies have confirmed that there is a causal relationship between the above risk factors and the degeneration and necrosis of dopamine neurons in the substantia nigra of the midbrain, and that preventive measures against the risk factors are definitely beneficial to preventing the onset and slowing down the progression of Parkinson’s disease. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. Primary prevention (no disease prevention) 1. People with family history of Parkinson’s disease and related gene carriers, and those who are exposed to toxic chemicals should be regarded as high-risk groups, and should be closely monitored and followed up with regular medical checkups, as well as strengthened health education and emphasized on self-protection. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 2. Increase efforts to protect the environment in industrial and agricultural production, reduce the emission of harmful gases, sewage and dirt, and strengthen labor protection for harmful workers. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 3.Improve drinking water facilities in rural areas and towns, protect water resources, reduce the pollution of rivers, reservoirs, ponds and wells, and ensure that the general public can drink safe and hygienic drinking water. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 4.Elderly people should be careful with phenothiazines, lisdexamfetamine and butyrophenyl drugs. 5, pay attention to the prevention and control of geriatric diseases (hypertension, high blood pressure, high blood sugar, cerebral atherosclerosis, etc.), enhance physical fitness, delay aging, prevent atherosclerosis, can play a certain positive role in the prevention of Parkinson’s disease. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. Secondary prevention (early detection, early diagnosis, early treatment) 1, early diagnosis. Parkinson’s disease has a long subclinical period, if we can carry out preclinical diagnostic techniques, such as olfactory dysfunction, PET scanning, mitochondrial DNA, dopamine antibody, cerebrospinal fluid chemistry, electrophysiology and other tests, to detect subclinical Parkinson’s disease as early as possible, and use neuroprotective agents (such as vitamin E, SOD, glutathione and glutathione peroxidase, neurotrophic factor, seligiline) to treat the disease, we may be able to slow down the whole clinical process. delay the entire clinical phase of the process. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 2, early Parkinson’s disease, although the substantia nigra and striatal nerve cells decrease, but dopamine secretion is compensatory increase, at this time the dopamine content in the brain is not significantly reduced, called the compensatory period, generally do not advocate the use of drugs, can be used in physical therapy, medical sports, tai chi, hydrotherapy, massage, qigong, acupuncture and other treatments to maintain the general daily work and life, try to delay the application of antitremor paralysis drug time. However, some people also advocate the early application of small-dose levodopa to reduce complications, which should be used on a case-by-case basis and on an optimal basis. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 3, Parkinson’s disease loss of compensation should be treated with medication. Tertiary prevention (slowing down the progression of the disease, preventing disability, improving the quality of life) 1, active non-pharmacological such as physiotherapy, body therapy, acupuncture, massage and other and Chinese and Western medicine drugs or surgery and other integrated treatment, in order to slow down the progression of the disease. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 2, pay attention to psychological guidance appeasement and spiritual care, ensure adequate sleep, avoid emotional tension and excitement, in order to reduce the triggering factors of aggravation of myoclonus. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 3, actively encourage patients to take the initiative to exercise, such as eating, dressing, washing and so on. For those with speech disorders, they can make efforts to practice pronunciation loudly in front of the mirror. Strengthen the joints, muscle activity and labor training, as far as possible to maintain the function of limb movement, pay attention to prevent falls and limb deformity disability. Stem cell therapy for Parkinson’s disease is a major medical breakthrough. 4, long-term bedridden, should strengthen the life care, pay attention to cleanliness and hygiene, turn over and pat the back diligently, to prevent fall pneumonia and bedsore infection and other complications, Parkinson’s disease, most of the deaths of the lungs or other systems such as the urinary system and other infections. Pay attention to diet and nutrition, give nasal feeding when necessary, and keep the urine and feces unobstructed. In order to continuously strengthen the body, improve the immune function, reduce the mortality rate.