Patients with AIDS may develop a rash in the acute phase as well as in the late onset of the disease, i.e., 2-3 weeks after infection with HIV, or several years after infection, which may manifest as blisters, papules, macules, and skin nodules and skin plaques, etc. 1. Acute phase rash: Red or reddish-brown macules may appear on the skin surface, preferably on the head, face, neck, forehead, back, extremities or genitals, etc., and may There may be slight pressure pain, fever and other symptoms, and it may also be accompanied by joint pain, swollen lymph nodes, fever, nausea and vomiting, diarrhea and other symptoms, but the degree of symptoms is mild. Usually it will subside on its own within 1-3 weeks; 2. Late rash of infection: red rash will also appear on the body surface, which is often more related to fungal infection of the skin, eczema, allergy, seborrheic dermatitis, etc. Symptomatic treatment must be actively carried out. If not treated in time, the rash may persist for a long time and even cause other undesirable complications. Patients need to follow medical advice for active treatment and control after the diagnosis of AIDS, and try to keep the condition at a stable level to prevent other complications or infections that may cause more damage to health.