It cannot be said that tuberculosis is the primary cause of death from AIDS. Tuberculosis is caused by Mycobacterium tuberculosis, and although Mycobacterium tuberculosis is one of the pathogens that patients with advanced AIDS are prone to secondary infection, in addition to this, a wide variety of bacterial, viral, and fungal infections, and malignant tumors, can accelerate the death of patients with AIDS. Due to the massive destruction of CD4-T lymphocytes by HIV, the body’s immune function is impaired, such as respiratory infections with Mycobacterium tuberculosis, which can lead to tuberculosis, thereby accelerating the progression of AIDS and shortening the life span of AIDS patients. In addition, other lung infections such as Pneumocystis jirovecii pneumonia are also common in patients with AIDS. Patients with AIDS who have recurrent fever symptoms should go to the CDC for X-ray, lung biopsy and other relevant tests to clarify the situation. After diagnosis, if the CD4 level is high, anti-tuberculosis treatment can be given first, and then anti-HIV treatment can be given after the anti-tuberculosis treatment course is finished; if the CD4 level is low, anti-HIV and anti-tuberculosis treatment need to be given at the same time to prevent the disease from deteriorating. Since some anti-tuberculosis drugs and anti-HIV drugs may interact with each other, treatment should be carried out under the guidance of an experienced doctor and in accordance with the actual situation.