The morbidity and mortality rate of patients with severe anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis ranges from 2.9% to 9.5%. The morbidity and mortality rate in patients with anti-LGI1 antibody-associated encephalitis is 6%. Different types of autoimmune encephalitis-associated antibodies cause different sites of central nervous system involvement and vary in disease severity and prognosis, with an approximate average mortality rate of 6%.