Apathetic hyperthyroidism belongs to a special type of hyperthyroidism, the cause of this disease is unclear, may be due to the long-term failure to properly diagnose and treat hyperthyroidism, the body is seriously depleted; or due to sympathetic nerve insensitivity to thyroid hormones, as well as catecholamine depletion, in recent years, some people believe that it may be related to magnesium deficiency. Apathetic hyperthyroidism is mostly seen in middle-aged and elderly people, and is especially common in the elderly. It has its own special clinical manifestations, and its diagnosis is based on the following aspects: 1. Patients sometimes have sunken eyes, dull eyes, or even droopy eyelids; there are no eye signs of protruding and gleaming eyes. 2. The thyroid gland is usually small, not easily palpable, or has nodules. 3. The skin is less sweaty, dry, cooler, wrinkled, harder, and often stained with pigmentation; the facial subcutaneous fat is less and accompanied by muscle atrophy. 4, mental symptoms: such as emaciated feeling, no obvious emotional ups and downs, indifferent expression; no interest in the surrounding things, do not care; have obvious melancholy state, mental activity is sluggish; answer questions flaccid, or have a short period of inattention; no muscle tremor, and there is a tendency to reduce movement. 5.Muscle wasting: there is often severe proximal myopathy, involving the shoulder and medullary muscles. 6.Heart condition: heart rate increases insignificantly, those greater than 100 beats/min are rare, the heart tends to enlarge, heart failure is more common, heart beats are often not particularly strong, transient or persistent atrial fibrillation may occur, and premature ventricular contractions may also be present. The patient may rapidly enter a semi-rigid state or coma, the body temperature is not very high, the heart rate may not be too fast, unlike the general hyperthyroidism crisis as agitation, there may be delirium. 8. Laboratory tests: The rate of 131 iodine uptake in the thyroid gland is often mildly increased in hyperthyroidism. The basal metabolic rate is also increased. Overall, the changes in thyroid function in this disease are not as dramatic as in typical hyperthyroid patients, but there are definitely abnormalities, and the key to diagnosis lies in the clinical recognition of this type.