Combination of Chinese medicine with surgery and chemotherapy

  In October 2003, a female patient from abroad came to the clinic. The patient was 56 years old, complained of loss of appetite for 3 months, epigastric discomfort, poor stool, once every 2-3 days, local gastroscopy showed irregular mucosal elevation in the gastric sinus, biopsy pathology: medium differentiated adenocarcinoma of the gastric sinus. He was worried that his body was weak and could not tolerate the surgery, so he came to the clinic and asked for Chinese medicine to regulate the treatment.  For gastric cancer, surgery is still the main means of possible cure, so if the patient’s health allows, surgical resection should be considered. The patient’s worries are also justified. She has not been able to eat normally for several months, and she is undernourished and in poor spirits, so she should do some preoperative preparations to undergo a major surgery, and a suitable herbal compound can promote gastrointestinal peristalsis, improve appetite and increase food intake, so that her nutritional status will improve and her spirits will improve, which will facilitate the surgery.  Seven days later, the patient had a second consultation and complained that after taking the medicine, her appetite improved, her food intake increased, her stools were smooth, her upper abdominal discomfort was relieved, and her spirit improved significantly. The patient saw hope and asked if she could just take Chinese medicine treatment without surgery in this case, as Chinese medicine is quite effective. We thought that she needed a comprehensive treatment combining Chinese and Western medicine, and surgery could be used and should be applied. We suggested the patient to receive surgery, and gave 7 patches of Chinese medicine orally. The patient underwent radical surgery for gastric cancer at the Cancer Hospital 4 days later.  On the 7th day after the operation, the patient came to the clinic with the help of his family members, and this was the third consultation.  Many patients think that after surgery, everything will be fine and they think they will be cured. We often warn patients that for tumors, surgery is only the first step in the long march, but there is still a long way to go, and they still need serious treatment, some of which need to be combined with chemotherapy, but herbal treatment is very important. We often see that patients have a high possibility of recurrence and metastasis six months to two years after surgery. Preventing recurrence and metastasis after radical surgery is a very important and arduous task, and if not handled well, all previous work will be lost. In our opinion, tumor disease is a kind of systemic disease, and local lesion is only a local manifestation of systemic disease, surgical resection only solves the local problem, but does not change the state of the whole body. How to change this condition, taking traditional Chinese medicine is a possible choice. Our early experimental research supports this view. Some of the classical prescriptions of Chinese medicine have anti-mutagenic and anti-initiation effects, and through the treatment of traditional Chinese medicine, the patient’s sensitivity state to carcinogenic and mutagenic agents can be reduced, thus preventing tumor reoccurrence. As for patients who have just experienced the trauma of surgery, what they urgently need is to recover their body, resume normal diet and restore their righteousness. Therefore, there are differences in taking Chinese medicine compound prescriptions at different stages and under different circumstances with different Chinese medicine dialectics.  After taking 7 patches of herbal medicine after the operation, the patient came to the clinic for the fourth consultation, walked into the clinic by himself, his spirit and strength improved, his food intake increased, his stool was once a day, he still felt discomfort in the upper abdominal incision, his pulse was stringent and thin, his tongue was thinly coated with white fur, his tongue was light red, and his sides were posteriorly dentate, the pathology report of the operation, medium differentiated adenocarcinoma of the gastric sinus, invading the whole layer to the extra-plasma membrane adipose tissue, there were cancer emboli in the pulses, the nerves were not invaded, the lymph nodes of the small curvature of the stomach were 2/5 positive and The lymph nodes in the small curvature of the stomach were 2/5 positive, the lymph nodes in the large curvature were 0/4 negative, and the lymph nodes in the pylorus were 0/5 negative. The patient was diagnosed as having spleen deficiency and toxin aggregation. The treatment was to strengthen the spleen and benefit the qi, detoxify and soften the firmness, and a small amount of detoxifying and softening drug was added to the previous prescription and 14 patches were given orally. The oncology hospital proposed to give systemic chemotherapy to the patient.  For progressive gastric cancer, postoperative chemotherapy is necessary. For progressive gastric cancer, even with radical surgery, micro-metastases exist in the body, and timely adjuvant chemotherapy can kill micro-metastases and reduce the chance of recurrence and metastasis, but because the current chemotherapy drugs are less selective and cause damage to the bone marrow system, digestive system, peripheral nervous system, etc., clinical attention should be paid to a series of side effects of chemotherapy and the tolerance of the human body. The human body’s own tolerance. In our opinion, chemotherapy can be incorporated into the aspect of eliminating evil in the theory of tumor in Chinese medicine, and be regarded as a means to eliminate evil, and be applied on the basis of eliminating evil without harming the righteousness, and the righteousness can still be restored, and be applied in combination with methods to support the righteousness.  In early December 2003, the patient came to the fifth consultation, complaining of nausea and vomiting just after the first chemotherapy treatment in the cancer hospital, and now he has loss of appetite, feeling of fullness in the upper abdomen, numbness in the fingers and toes, and the bowels have not been relieved for 3 days.  After chemotherapy, patients are prone to nausea, epigastric distension, vomiting, diarrhea or constipation, loss of appetite, etc. These are gastrointestinal reactions. Before and after chemotherapy, applying Chinese herbs to tonify the liver and spleen, harmonize the stomach and subdue rebelliousness to maintain a good appetite and a smooth digestive tract is an effective way to reduce gastrointestinal reactions. The theory of qi and blood is one of the effective methods to guide the prevention and treatment of chemotherapy side effects in the blood system, such as anemia, leukopenia, and thrombocytopenia after chemotherapy, etc. According to the theory of Chinese medicine, “qi is the master of blood, blood is the mother of qi”, “the spleen and stomach are the source of qi and blood biochemistry”, and “the kidney is the master of bone and marrow”. According to the theory of Chinese medicine, “qi is the master of blood, blood is the mother of qi”, “spleen and stomach are the source of qi and blood biochemistry”, “kidney is the master of bone and marrow”, the application of drugs to benefit qi and nourish blood, strengthen spleen and kidney can make the patient’s tolerance increased and the bone marrow suppression improved. For the damage to the nervous system, the rational application of blood activating and blood stasis removing drugs is one of the effective ways to effectively prevent and control the neurological side effects during chemotherapy. With the clinical application of phytochemical drugs or oxaliplatin and other drugs, patients often feel numbness and even pain in the tips of fingers and toes or palms and dorsum of feet, and we identify the pathogenesis of their pathogenesis according to the main symptoms of the patients mainly as “qi deficiency According to the main symptoms of the patients, we can identify the pathogenesis of the disease as “Qi deficiency, blood stasis, cold blockage”, and take the method of “activating blood stasis, warming the meridians and clearing the ligaments”, such as Danshen, Red Peony, Peach Seed, Lingxiao Flower, etc., or combine with the application of warm kidney Yang drugs, which can achieve certain effect. We attach great importance to the guiding position of TCM theory in the understanding and treatment of tumor, and emphasize that the formulation of tumor treatment plan is guided by TCM theory and the combination of Chinese and Western medicine, without excluding any effective method, but in accordance with the holistic concept of TCM, dialectical treatment, focusing on the combination of the universal law of tumor and individualized treatment, so as to benefit the patients most.  After palliative surgery, the amount of tumor in the patient’s body is obviously reduced, and the body faces both opportunities and challenges. The opportunities are that if the patient can resume eating as soon as possible, increase nutrition, enhance the body’s immune control ability, and inhibit the growth of residual tumor, the patient can stabilize the disease for a longer time and obtain a longer survival period; the challenges are that if the body’s control ability is poor, the residual tumor may proliferate at a high speed and the tumor will dominate again in a short period of time. The challenge is that if the organism is poorly regulated, the residual tumor may proliferate at a high rate, and the tumor will again appear to dominate, which will produce complications and pose a greater threat to the organism. Our clinical experience shows that after palliative surgery, if combined with appropriate chemotherapy and adherence to proper Chinese medicine treatment, similar effect of radical surgery can be achieved.