Recently, many patients have asked the question of mouthwash, here, I downloaded from the Internet, organized a write related information for patients and friends to read, I hope it will be helpful to patients. General gargle with clean water gargle. To assist in the prevention and treatment of oral diseases and complications, a solution with certain drugs is commonly used as a gargle solution. The use of pharmaceutical rinses can effectively inhibit plaque formation and improve the inflammatory condition of the gums. Drug rinses should have the following characteristics: ① no oral and gastrointestinal toxicity; ② not absorbed by the gastrointestinal tract; ③ effective; ④ a wide range of antibacterial spectrum; ⑤ low drug tolerance induction. When gargling, let the mouthwash reach every corner of the mouth through cheek and tongue movements, and stay for a certain period of time, mostly 30 seconds, and spit out after a period of time, mostly 30 minutes, and then rinse with water or brush teeth, etc. Triclosan is a mild antimicrobial drug, chemically known as triclosan, also known as Jade Pure, DP300, triclosan, widely used in soaps, deodorants, disinfectant hand soaps and surgical instrument soaks. 1990 Williams first reported the effect of the application of gargles containing triclosan, triclosan as a new Triclosan is a safe and efficient broad-spectrum antimicrobial agent, which has a high inhibitory effect on harmful bacteria in the oral cavity and can directly inhibit the production of inflammatory mediators without irritation or bitterness; it has become the most used mild non-ionic antimicrobial agent among the gargles marketed in western countries. After years of research, it has been confirmed that it has significant efficacy on gingivitis, periodontitis and oral infections, and also eliminates bad breath, does not lead to tooth discoloration, no bad taste, thus confirming its new status in oral care products. 2, tea polyphenol Tea polyphenol (tea′ s polyphenol , TPP) is a complex of polyphenolic compounds extracted from tea leaves. Research has confirmed that a certain concentration of tea polyphenols can inhibit or reduce the number of plaque and its adhesion on the dental surface. Tea polyphenols for oral care have the advantages of low cost, abundant source, safe and reliable, no obvious pigmentation, no accumulation toxicity and genotoxicity etc. Tea has anti-caries effect. With the in-depth research on the role of tea polyphenols on oral caries-causing bacteria and plaque, the role of tea polyphenols in anti-caries has been paid more and more attention. Chlorhexidine, also known as chlorhexidine, is the most widely used drug with the strongest antibacterial ability. The concentration of rinse solution is 0.1%~0.5%, and the effective antibacterial concentration is 100ug/ml~0.1ug/ml, and it can completely inhibit the formation of plaque. Chlorhexidine has a stronger inhibitory effect on gram-positive bacteria than gram-negative bacteria. The disadvantage of chlorhexidine is that it causes tooth surface and tongue mucous membrane coloring and bitter taste, and may also cause taste disorder. 4, antibiotics The most commonly used antibiotic rinse [7] are 0.01% to 0.03% metronidazole and 0.06% tetracycline. Metronidazole is a potent drug for specialized anaerobic bacteria, which can effectively inhibit plaque formation and improve the inflammatory condition of gums. Tetracycline is effective against actinomycete symbiotic actinomycetes, and also against Bacillus gingivalis and Veronella. In addition, fluoride such as 1.65% SnF2, 0.01%-0.03% furacilin rinse, bloodroot base rinse, and zinc salt rinse have been shown to be effective in inhibiting plaque. The use of drug rinse rinse is a certain therapeutic effect, drug rinse rinse is generally used after periodontal cleaning and periodontal surgery, and hospitalized patients with oral tissue complications, but we should pay attention not to chlorhexidine and antibiotic rinse rinse rinse rinse as a daily necessity, can not be used as a long-term gargle rinse rinse, when the oral tissue complications healed, should stop using, so as not to cause the normal oral flora imbalance and develop drug tolerance. Gargling with a gargle solution containing triclosan and tea polyphenols is not harmful to oral tissues for a long time. In addition, it is important to note that rinses are not a substitute for brushing. Plaque is constantly formed in the mouth, and new plaque will appear after cleaning the tooth surface, so we should develop the good habit of brushing our teeth in the morning and evening and rinsing our mouth after meals and keep it for a lifetime, that is, we should remove plaque continuously and thoroughly throughout our life. I wish you all good teeth, good appetite, good health and good food!