Granny Lai is 76 years old and has been troubled by tongue pain repeatedly for the past two years. She went to all the major hospitals in Guangzhou and underwent many tests, worrying if she had an unknown cancer, but the final test results did not reveal anything. It turns out that Granny Lai has a Chinese medicine disease called “Tongue Pain”, which is known as “Burning Mouth Syndrome” in Western medicine. The burning mouth syndrome is a group of symptoms with burning pain in the oral mucosa as the main manifestation, the general description of the patient is a hot pain, accompanied by dry mouth, tongue numbness, taste changes, etc., often no obvious clinical damage characteristics, but the symptoms are strong, the case of Granny Lai is such, repeated severe tongue pain, the examination can not find the cause, the constant pain and drive the elderly to seek medical advice everywhere. “Many patients develop anxiety, depression, and hypochondria (including fear of cancer) as a result, and the disease is more prevalent in menopausal or postmenopausal women, with a higher incidence in women than in men.” This disease is often accompanied by endocrine changes and psychological disorders, and in recent years the incidence of alterations has been increasing year by year, and has been the third most prevalent oral mucosal disease. The cause of this disease is not yet clear, and there is no special treatment drugs and methods. Chinese medicine has its own set of dialectical treatment theories and methods. According to Chinese medicine theory, the disease is related to emotional and mental disorders, dietary disorders, disorders of labor and relaxation, and physical weakness in old age, and most patients’ symptoms can be improved or even cured through dialectical conditioning, psychological guidance, dietary regimen, and reasonable exercise. After treatment, Granny Lai’s burning tongue pain has been largely relieved through acupuncture and internal Chinese medicine. There are many ways to treat tongue pain in TCM, besides internal herbal medicine, acupuncture point posting, moxibustion, acupuncture, acupuncture and bloodletting, etc. Different treatments are given to different patients according to different dialectical evidence.