New methods to promote waking of vegetative patients need comprehensive treatment, including drug therapy, hyperbaric oxygen chamber therapy, physical therapy, Chinese medicine therapy, affection therapy, high cervical segment spinal cord electrical stimulation and deep brain stimulation therapy, etc. 1, drug therapy: routine application of drugs that nourish nerves, improve circulation and nourish brain cells, such as piracetam, cytarabine and other drugs, helps to promote wakefulness; 2, hyperbaric oxygen chamber therapy: hyperbaric oxygen can rapidly increase the oxygen content and oxygen storage in brain tissue, increase vertebrobasilar artery blood flow, which can increase the partial pressure of oxygen in the reticular activation system and brainstem, speed up the recovery of consciousness, thus maintaining the normal activities of vital functions 3. physical therapy: using exercise therapy, neuromuscular electrical stimulation, and physical therapy to promote the recovery of limb function and prevent complications, treating joint contractures with distraction techniques, and treating paralyzed limbs with passive joint activity training; 4. Chinese medicine treatment: through local acupuncture, or using brain-awakening herbal injections, such as Qing Kai Ling injection and Brain-awakening Jing injection, which help patients to awaken; 5. Affection therapy: family members can be allowed to chat and tell stories with the patient like normal people to stimulate the patient and promote awakening; 6. Stimulation therapy: including high cervical spinal cord electrical stimulation and deep brain stimulation therapy, the mechanism of promoting awakening of vegetative people is not clear, and it is generally believed that exogenous continuous electrical stimulation applied to the patient’s brainstem upstream activation system can improve the physiological electrical activity of the human brain, thus promoting awakening of consciousness.