There are many clinical conditions that cause toothache, which can usually be relieved by warm water rinses and simple pain medications such as aspirin, anti-inflammatory pain, and ibuprofen. If the toothache is accompanied by inflammatory manifestations, it may be related to inflammation such as periodontitis and gingivitis, and anti-inflammatory drugs such as metronidazole and tinidazole can be used to control the inflammatory response under the guidance of a doctor, which can relieve the pain. It is important to note that women during pregnancy should avoid taking metronidazole. In addition, you can also press and rub the Hegu point when you have toothache, which has the effect of relieving pain. If the toothache is not relieved or recurring after the above treatment, it usually indicates that the condition is more serious and cannot be relieved by general treatment, so it is suggested to consult a doctor as soon as possible to carry out causal treatment to solve the toothache fundamentally. 1.tooth decay: toothache caused by tooth decay is usually due to the large cavity on the surface of the tooth and the food residue inside stimulates the tooth nerve, at this time, taking painkillers or anti-inflammatory drugs can only temporarily relieve the toothache. The toothache is usually caused by bacterial infection in the root canal of the tooth, which causes inflammation of the tooth pulp tissue and leads to toothache. This usually requires root canal treatment to relieve toothache, and in severe cases, the affected tooth may need to be extracted; 3, tooth and gum sensitivity: people with tooth and gum sensitivity often experience more pronounced pain after eating hot and cold irritating food. For this type of patients, they should avoid contact with irritating food and use some desensitizing toothpaste when brushing their teeth to reduce irritation. It is also necessary to treat the primary causes of gum sensitivity, such as wedge-shaped tooth defects, cryptodontia, periodontal atrophy and many other pathologies, through specialist treatments such as scaling, dental implants and tooth extraction. In addition, patients with lesions such as trauma and gum tumors may also present with persistent toothache. In the presence of trauma, toothache caused by damage to the tooth structure should be promptly extracted and the bad tooth replaced with a dental implant in order to avoid causing infection. In the case of conditions such as gum tumors, it is usually necessary to remove the lesion. Some people believe that the trick of using stimulating items such as white wine and pepper water with gargle can treat toothache, but there are no relevant scientific studies to support this argument. So try not to take it to avoid irritating the oral mucosa or lesions. In daily life, we should pay attention to maintain oral hygiene, such as diligent brushing and rinsing, to avoid the residue of food on the surface of teeth or periodontal residue and accumulation. Also avoid eating stimulating or sugary food to avoid aggravating the manifestation of toothache.