Dear Professor Shan Yuan Dong, Hello! Many of the treatments for idiopathic thrombocytopenic purpura ITP are not satisfactory, and the treatment options are limited, even the patients themselves can talk about it; moreover, the current cytokines to raise platelets are not very satisfactory; so, if the patient has extremely low platelets with bleeding manifestations, is there any better way to raise platelets other than platelet transfusion? Thank you! The goal of treatment is not to see the platelets rise to normal, but to see that the patient no longer bleeds or does not bleed much after treatment, that is to say, even if there is a very light bleeding tendency, we still allow it, as long as the bleeding is not life-threatening. As long as the bleeding is not life-threatening, we think it is not a big problem. Therefore, most of our patients start with adrenocorticotropic hormone or high dose of intravenous gammaglobulin, if the platelets can rise after treatment, but most of them decrease again with the discontinuation or reduction of the drug. In some patients, even if the platelets are very low, we can not use the drug. Generally speaking, if the platelets can be maintained at about 30,000, it should still be relatively safe. Therefore, the vast majority of patients in this category do not need long-term maintenance treatment, as long as they pay attention to their own protection, such as the prevention of colds and flu do not overexert themselves, prevent trauma can go to work as usual to do some work that can be done.