Undifferentiated spondyloarthropathy is a chronic inflammatory disease that mainly affects the sacroiliac joints. The basic pathological change is tendon ligament attachment point inflammation, which can be associated with generalized joint pain and discomfort, low back pain, heel pain, coldness, eye and skin lesions, and in severe cases, systemic symptoms and even hyperthermia. It can develop at any age, has a high incidence, has an unclear etiology, and can develop into other connective tissue diseases. Most patients have a good prognosis if diagnosed and managed properly. Exercise has a therapeutic effect and is essential throughout the treatment process and in maintaining remission.
I. Intensive treatment (in the shortest possible time to achieve the above goals)
1. Hormones Prednisone, Depo-Provera, methylprednisolone, etc.
Features: can quickly eliminate inflammation and analgesia, significantly improve symptoms, control symptoms in the short term and improve patients’ quality of life. Inexpensive but to bear more side effects of drugs, as a bridge treatment is a good means of high dose medication small dose maintenance, early discontinuation of drugs.
2.Biologics Ixepro, prednisolone, Enzyme, classical gram, Xiomel and Yamiro
Characteristics: Rapid relief with few side effects, but more expensive and may be ineffective in some patients. Short-term use is possible if financial conditions allow.
II. Maintenance therapy (maintaining long-term disease control after the treatment has reached the standard)
1.Functional exercise is the main means
(1) Raise the level of biological hormones in patients’ bodies, which plays a certain therapeutic role and can reduce the use of drugs or no drugs.
(2) Preventing osteoporosis
(3) Maintain and improve joint function
(4) Pleasant mood and enhance physical fitness
Exercise method: choose one of the ways
(1) swimming: 1,000 meters per day (can be progressive)
(2) walking: 1 hour per day (continuous)
(3) running: 30 minutes per day (continuous)
2.Non-steroidal anti-inflammatory drugs Meloxicam, Loxone, Aceclofenac, Ciloxib, Etoricoxib, etc.
Features: It is a basic drug with anti-inflammatory and analgesic effect, the main side effects are gastrointestinal reactions, if there is no special can be used for a longer period of time, and the drug can be stopped after the condition is controlled.
3.Biotics: Ixeprop, Diazepam, Enzyme, Class A, Xumel and Yamiro, etc.
Features: rapid relief, small side effects, if economic conditions allow is currently the best choice in maintenance treatment, such as a biological agent is not effective can be converted to another, still effective, but close follow-up to screen for infection and other diseases.
4.DMARDs are palliative drugs, the main drugs are methotrexate, leflunomide, cyclophosphamide, mycophenolate, azathioprine, salazosulfapyridine and hydroxychloroquine sulfate, alamodex, tacrolimus, etc.
Features: Used for patients with peripheral joint and extra-articular manifestations, to be combined in cycles, can be increased or decreased in steps according to the condition and immune function status, most patients can discontinue the drug, and long-term follow-up observation after discontinuation.
Follow-up plan: close follow-up is the key to the treatment of undifferentiated spondyloarthropathies, in principle, patients “three to nine weeks” follow-up once. The follow-up period can be extended according to the condition of the patient after one year of treatment. After the visit, you must register the information in the outpatient clinic 339.
Caution: 1.
1. This disease is not directly related to “wind” and “damp”, and patients should not worry about fear of wind and cold.
2, no special dietary contraindications, but should avoid taking immunity-enhancing health products or proprietary Chinese medicine.
3, sleep on a hard bed, low pillow.