The selection of medication according to seizure type and syndrome classification is the basic principle of epilepsy treatment. The following factors should also be considered: contraindications to antiepileptic drugs, possible side effects, the time to reach the therapeutic dose, the number of doses taken and the appropriate dosage form, the needs of special populations such as children, women of childbearing age and the elderly, the interactions between drugs, and the source and cost of drugs. The decision will be made by the physician, patient and parents to maximize efficacy and minimize side effects, and to individualize medication. The type of seizures and epilepsy syndrome are closely related to the efficacy of antiepileptic drugs, such as some drugs are effective for partial seizures but can aggravate full-blown seizures, so a clear diagnosis is essential before selecting medication. A comprehensive understanding of the absorption, distribution and metabolism of drugs in the body as well as the toxic side effects of drugs is also of great significance. They determine the method of administration, starting dose, maintenance dose, number of doses, duration of treatment, addition and reduction of drugs, etc. of antiepileptic drugs, which are factors that must be considered when selecting drugs. For example, the therapeutic and toxic concentrations of phenytoin sodium are close to each other, and dizziness, drowsiness, unsteadiness, and behavioral changes can occur in cases of toxicity. Only in this way can the patient tolerate and comply as well as possible. Although children metabolize certain drugs quickly and tolerate them well, some drugs, such as phenytoin sodium, can affect bone development and some drugs have cognitive impairment, so they cannot be used; for the elderly, slow metabolism, poor tolerance, combined with a variety of diseases, and the chance of interaction between multiple drugs taken, easily affect the effective therapeutic concentration of drugs; young female patients should also Young female patients should also consider the effects of drugs on beauty, pregnancy, and fetus. The age, gender, and occupation of the patient are different, and the psychosocial needs of the patient should be considered when selecting medication. The degree to which epileptic patients are socially accommodated in social life, such as study, work, and recreation, is a criterion for the degree of improvement of the disease.