Sudden hives all over the body may be acute urticaria, which can be treated with topical and oral medications. Acute urticaria may be related to food, drugs, inhalants and infections, etc. The onset of the disease is rapid, often starting with itching of the skin, and soon appearing as normal skin color, bright red or pale white masses. 1. Topical drugs: patients can use topical glycerin lotion, if the itching symptoms are serious, can be used topically glucocorticoid ointment, such as mometasone furoate ointment to stop itching. 2. Oral drugs: oral drugs are generally preferred to the second generation of non-sedating antihistamines, commonly used drugs include cetirizine, levocetirizine, loratadine, diclofenac tadalafil, ibastine and so on. All of the above drugs should be used under the guidance of a professional doctor to avoid self-medication. If you suddenly get hives all over your body, and if you experience symptoms such as chest tightness, wheezing, edema of the larynx, and difficulty in breathing, you need to call the emergency number immediately and go to the hospital for medical treatment.