Complete rectal prolapse is a condition in which the rectoanal canal or even part of the sigmoid colon is displaced and descends and exsanguinates. It is mostly prolapse of the full rectum and sigmoid colon. Rectal prolapse is a more serious disease in anorectology and is not uncommon, with an adult incidence of 0.4 to 2.1% of anorectal diseases. Rectal prolapse is a more common anorectal disease, which seriously affects the quality of life of patients. Complete rectal prolapse requires surgical treatment, and there are many clinical surgical methods, each with its own advantages and shortcomings. How to improve the efficacy of surgery and reduce recurrence and postoperative complications is still the focus of clinical attention. From 1998 to 2008, our department adopted a modified quadruple procedure (rectal mucosal segmental longitudinal penetrating suture + rectal submucosal punctal injection + perirectal gap injection + anal double-line loop reduction) to treat 33 cases of complete moderate to severe rectal prolapse with good results. At present, the general treatment principle for complete rectal prolapse is to fix the prolapsed rectum with the surrounding tissues, suture and strengthen the relaxed pelvic and anal sphincter groups, and fix the lower part of the sigmoid colon with the rectum, so that the rectum can be restored to the normal state without causing complications and sequelae and without recurrence. For adult rectal prolapse, especially complete rectal prolapse, the recurrence rate is high and complications are many after taking single treatment. At present, most clinicians believe that a combination of procedures should be used in order to achieve ideal results. In order to explore the treatment methods and approaches for complete rectal prolapse, we designed a modified surgical approach to reduce the recurrence rate, complications and sequelae of the surgery in accordance with the morbidity characteristics of rectal prolapse. We used a quadruple treatment of rectal mucosal segmental longitudinal penetrating suture + rectal submucosal dot injection + perirectal gap injection + anal double-wire loop reduction to strengthen the anorectum and sigmoid colon. Conclusion The quadruple procedure for complete rectal prolapse is a treatment method with high cure rate, less complications, less pain and faster recovery, which is in line with the “minimally invasive” and “painless” concepts advocated by modern medicine. It is in line with the concept of “minimally invasive” and “painless” advocated by modern medicine. This quadruple procedure is theoretically in line with the current treatment principles for complete rectal prolapse, and has achieved very satisfactory clinical results.