The fetal membranes are tightly attached to the uterine wall and surround the fetus and amniotic fluid, providing protection to the fetus. Normally, the membranes rupture during labor and the fetus is delivered, but when the membranes rupture before labor, it is called premature rupture of membranes. There are many reasons for premature rupture of fetal membranes, including: (1) infection of the reproductive tract, which can cause pathogenic microorganisms to travel up to the fetal membranes and cause fetal membranes to rupture; (2) increased pressure in the amniotic cavity, which can lead to increased intrauterine pressure in twin pregnancies, excessive amniotic fluid, and giant babies, which can lead to rupture at weak points in the fetal membranes; (3) uneven stress on the fetal membranes, which can lead to uneven stress on the fetal membranes for various reasons. (4) lack of nutritional factors, when the lack of vitamin C, zinc and copper, can make the fetal membrane resistance decreased, easy to cause premature rupture of fetal membrane; (5) improper amniocentesis, artificial membrane stripping, frequent sexual life in late pregnancy may lead to premature rupture of fetal membrane. After premature rupture of fetal membranes, pregnant women mostly feel a large amount of fluid discharged from the vagina suddenly, but there are also high level water breakage, only a small amount of fluid discharged from the vagina should be more attention. If left untreated, it may lead to preterm labor, placental abruption, amniotic fluid, umbilical cord prolapse, fetal distress and neonatal respiratory distress syndrome, and the rate of maternal and fetal infection and perinatal death increases significantly.