Premature rupture of membranes includes two categories of expectant therapy and termination of pregnancy, the details are as follows: 1. Expectant therapy: no signs of infection before 35 weeks of pregnancy, antibiotics can be applied to prevent infection, quiet bed rest and keep the vulva clean. Close monitoring of body temperature, fetal heartbeat, total white blood cell count and classification, serum C-reactive protein and culture of cervical secretions. For those who need to terminate pregnancy at <34 weeks of gestation, apply glucocorticoids to promote fetal lung maturation when infection is excluded, use contraction inhibitors if there are regular contractions or the opening of the uterus is wide, prolong the pregnancy for 24-48 hours as much as possible so that the glucocorticoids can take effect after delivery to improve the prognosis of preterm infants, and use antibiotics to prevent infection, and wait for spontaneous delivery if there is no prodromal labor and no signs of infection in those who have broken membranes. After 36 weeks of gestation, if the membranes have broken for more than 12 hours, antibiotics can be used to prevent infection; 2. Termination of pregnancy: after 35 weeks of gestation, if the membranes have broken in the first position and are not in labor and there are no signs of infection, natural labor can be awaited. After 36 weeks of gestation, if the membranes have broken for more than 12 hours, antibiotics should be used to prevent infection and induce labor. Once intrauterine infection occurs, terminate the pregnancy immediately regardless of gestational age. If vaginal delivery is not possible within a short period of time, pregnancy should be terminated by cesarean section.