Chickenpox is caused by the varicella-zoster virus infection. The varicella-zoster virus belongs to the family of herpesviruses and causes a bean-like rash on the skin after initial infection, accompanied by fever, malaise, and loss of appetite, among other complications. Acyclovir is a common broad-spectrum antiviral drug, belonging to the nucleoside class of antiviral drugs, has a certain inhibitory effect on varicella-zoster virus, and its side effects are relatively small. During chickenpox, if the local herpes symptoms are severe, topical treatment with acyclovir solution can effectively relieve chickenpox symptoms, and the ointment made of acyclovir as the main ingredient is easy to use and long-lasting, and is a common antiviral drug for the skin of patients with severe chickenpox. Acyclovir eye drops can be applied to varicella herpes around the eyes.