Early symptoms of breast cancer are as follows: 1. Although some early breast cancer patients are not able to touch a clear lump in the breast, they often have local discomfort, especially postmenopausal women, who sometimes feel mild pain and discomfort in one breast, or sinking and soreness in the back of one shoulder, even involving the upper arm of that side. 2, early breast can be touched in the size of a bean lump, hard, movable. Generally there is no obvious pain, occasionally there is paroxysmal hidden pain, dull pain or stabbing pain. 3, breast shape changes: visible skin elevation at the lump, some local skin orange peel, or even edema, discoloration, eczema-like changes, etc. 4. The nipple is near the center accompanied by nipple retraction. The skin of the breast is mildly depressed (medically called “dimples”), the nipple is eroded, the nipple is asymmetrical, or the skin of the breast is thickened and thickened, and the pores are enlarged (medically called “cellulite”). 5, nipple overflow: special attention should be paid to further examination when the overflow is bloody or plasma blood. 6. Regional lymph node enlargement, with the most common being ipsilateral axillary lymph node enlargement. If the supraclavicular lymph nodes are enlarged, it is already in advanced stage. In addition, estrogen is one of the prerequisites for the development of breast tumor. The onset of breast cancer ranges from 18 to 70 years old, mostly between 30 and 60 years old, especially the reproductive period and menopause are the high incidence stages of female breast cancer. Women who have used estrogen replacement therapy for more than 10 years should be closely monitored and genetic screening should be performed if available.