Patients with blood uric acid 498μmol/L can reduce blood uric acid through dietary adjustments, lifestyle changes and medication. 1. Dietary adjustments: patients with blood uric acid 498μmol/L should pay attention to a low purine diet, try to avoid animal offal, seafood, broth and other high purine content of food, and avoid drinking alcoholic beverages, pay attention to increase the amount of daily water intake. 2. Lifestyle changes: patients with high uric acid should avoid staying up late, quit smoking, quit drinking, overweight patients should reduce their weight and avoid strenuous exercise. 3. Drug therapy: patients with blood uric acid 498μmol / L if there are gout attacks, uric acid kidney stones, hypertension, stroke, obesity, glucose intolerance or diabetes, renal hypoglycemia, cardiac insufficiency and other conditions should also be under the guidance of a physician to take febuxostat, allopurinol and other uric acid-lowering medications to control the level of blood uric acid. Drugs should be used under the guidance of a physician, it is recommended that patients with increased uric acid to the rheumatology and immunology department of a regular hospital for detailed consultation, and follow the doctor’s instructions for treatment.