Lipomas appearing in many places on the body belong to multiple lipomas, which are common body surface swellings. Although there is a possibility of malignant transformation, they can usually be cured after timely excision. Multiple lipomas are generally not scary. Multiple lipomas are often symmetrical, small tumors, may have a family history, the tumor body is normal fat-like tissue, preferably in the limbs and trunk, located in the deeper part of the body may undergo malignant transformation, and should be resected in a timely manner. Lipoma resection often adopts lumpectomy, under local infiltration anesthesia, complete resection of lipoma body and peritoneum as possible, which can cure the lipoma and effectively prevent the recurrence of lipoma. Lipoma grows slowly, but it can grow to a huge size, so it is suggested that patients with lipoma should have it removed as soon as possible to avoid aggravation of the condition.