The treatment of ascites in cirrhosis should first clarify the cause of ascites formation and its nature. If it is simple ascites caused by water and sodium retention, attention should be paid to rest, low sodium diet and appropriate use of diuretics. If the cause of ascites is often multiple, such as hypoproteinemia, abdominal infection, etc., the complications should be actively corrected along with diuretic therapy: supplementation of human albumin, anti-infection, etc. If the amount of ascites is large, it is feasible to release ascites by laparotomy or to perform concentrated ascites retransfusion. For recalcitrant ascites, surgical treatment such as TIPS can be considered, and if patients have obvious arteriovenous fistula, interventional treatment can also achieve better results. In conclusion, the treatment of ascites in cirrhosis should be actively liver-protective and diuretic at the same time to clarify whether there are other causes, symptomatic treatment, comprehensive treatment, and accurate recording of 24-hour urine volume to quantify the diuretic effect and adjust the medication at any time.