There is no such thing as the most effective medicine for proctitis. The causes of proctitis include bacterial infection, unclean sex, and severe constipation. Patients need to go to the gastroenterology department of the hospital for examination and take medication according to the causes of proctitis. In general 1. Bacterial infection: patients may suffer from local long-term inflammation without treatment, leading to bacterial infection producing proctitis. At this time, patients can take oral amoxicillin capsules, levofloxacin tablets, metronidazole tablets and other drugs under the guidance of the doctor for treatment. 2. unclean sex: patients who have anal sex behavior, at the same time have more than one sexual partner, etc., may also induce proctitis. At this time, the patient needs to immediately stop unclean sex, keep the anus clean and hygienic, can be under the guidance of the doctor oral levofloxacin tablets, ciprofloxacin tablets and other drugs for anti-inflammatory and anti-infection treatment. 3. Severe constipation: When the patient is severely constipated, the hard fecal matter may scratch the mucous membrane of the rectum in the process of excretion, causing proctitis. At this time, patients need to take oral mesalazine enteric-coated tablets, metronidazole tablets, amoxicillin capsules and other anti-inflammatory drugs under the guidance of a doctor, and in severe cases, you can take the treatment of enemas in the gastroenterology department of the hospital. If you suffer from proctitis, you should follow the doctor’s instructions in time to carry out the relevant examination and treatment, the use of drugs should also follow the doctor’s instructions.