Red dots on the tongue are most commonly due to mycotic papillitis. The four types of tongue papillitis include filiform papillitis, mycotic papillitis, contour papillitis, and lobar papillitis. Filiform papillitis has atrophic damage as the main manifestation, while the other three have pain, congestion, redness and swelling as the main signs and symptoms. Mycotic papillitis has a smaller number of papillae, is red in color, and is distributed in the anterior and apical parts of the tongue; mycotic inflammation is not common. They show swollen, congested, burning papillae with thin and deep red epithelium, strawberry-like changes, and significant pain. Malnutrition, anemia, hematological disorders, fungal infections, antibiotic abuse, endocrine disorders, and vitamin deficiencies are factors in the systemic pathogenesis. Local factors include over-sharpened tooth tips, tartar, poor restorations, and traumatic stimuli such as eating spicy or overly hot food, infection, etc. First of all, treatment should be directed to the cause. The presence of irritating factors around the lesion, such as over-sharp cusps and poor restorations, should be removed promptly. For obvious swelling and pain can be treated with oral or local anti-inflammatory drugs. Treatment can be done with Chinese medicines that clear heat and detoxify the toxin, for example, stomatitis clear granules, etc. 0.1% to 0.2% chlorhexidine gluconate solution, compound boric acid solution, 0.1% epsilon solution for mouth rinsing, and also lysozyme tablets and waxer tablets for containing. For specific medication, please refer to the clinical situation and follow the guidance of the doctor’s interview.