The two corners of the mouth are white, usually considered to be stomatitis or vitiligo, need to be diagnosed according to the clinical symptoms of the cause, and then treatment. The actual fact is that you will be able to get a lot more than just a few of the most popular and popular items. It can be supplemented with vitamins, folic acid, etc., with the use of chlorhexidine acetate solution wet compresses when there is crust; 2, vitiligo: due to the destruction of melanocytes resulting in skin white spots, manifested as limited or generalized skin white spots, the corners of the mouth common. If it is found that the corner of the mouth white, accompanied by other parts of the body appear milky white or porcelain white patches of white, then it is considered vitiligo. Glucocorticoids are commonly used to control the progress of the disease and prevent gradual aggravation of the disease. Denide cream and hydrocortisone ointment can be used topically to prevent the spread of the white spots and help restore the skin color, which can be applied simultaneously with tacrolimus ointment or pimecrolimus cream to reduce the adverse reactions such as capillary dilation and skin atrophy caused by long-term topical glucocorticoids.