Sex, an important part of a couple’s life together, but when life is threatened, breast cancer patients and families are sensible enough to choose another way of expressing love, using sexual repression instead of sex to express our deepest desire and love, which is scientific? Is it reasonable? The answer is no. In the clinical work, we often encounter these doubts and questions, such as “will married life lead to the recurrence of breast cancer”, “is sex harmful to the patient’s body”, “will the tumor be transmitted through sexual life? “etc. On the contrary, a moderate, harmonious and regular sex life is not only harmless to the body, but also can enhance the patient’s self-confidence, help maintain the balance of the patient’s endocrine function, improve the immune function of the body, as well as harmonize the relationship between husband and wife, enhance the patient’s confidence to overcome the disease, and help the patient recover. It can also improve the relationship between husband and wife, enhance patients’ confidence in overcoming the disease, and facilitate their recovery, and even effectively prevent the recurrence of breast cancer. Because tumor disease is not an infectious disease, it will not be transmitted to each other through sexual life. The recovery of sexual ability also reflects the recovery of the whole body from the other side. A 39-year-old patient with right breast cancer had a mastectomy and reconstructive surgery, chemotherapy and endocrine therapy. Ovarian denervation led to premature menopause, vaginal dryness and difficulty with intercourse, she became sexually frigid and avoided sex, leading to disharmony in the couple. A diagnosis of sexual dysfunction was made. The patient said that she never thought about sex, completely lacked sexual fantasies and avoided her husband’s offers. The loss of normal sexual function at this age caused her to feel guilty and distressed, and this emotion pervaded her entire mind. The patient has severe painful intercourse, even with the use of lubricants. Breast cancer treatment and its side effects may affect your sex life and how you see yourself. However, these effects can often improve gradually after treatment, so don’t think about no more sex in your life and try to be happy, although some women may take a long time to recover. Sexual dysfunction covers psychological, physical, interpersonal and physiological areas of problems and is a common problem after cancer treatment. It is therefore not surprising that up to 90% of breast cancer patients are diagnosed with sexual dysfunction after treatment, and some reports even show that almost all women have some form of sexual problem after breast cancer treatment. In actual clinical practice it is difficult for physicians to discuss solutions with patients in a short period of time. However, sex is an important part of most women’s lives, and breast cancer patients are no exception. This article will highlight the common problem of sexual dysfunction and how to deal with this problem. The reasons for altered sexual desire after breast surgery are psychological in nature and include changes to one’s image, self-confidence and body, local insensitivity and sensory hypersensitivity caused by the surgery. After mastectomy, breast cancer patients often have concerns and worries about their physical beauty and even think that they are no longer “fully” female and worry whether their husbands still love them. Patients often feel a sense of loss and inferiority, and their hearts are full of contradictions and sorrow. They lose confidence in sexual expression and become passive in sexual life, which may develop into sexual indifference and affect the harmony of sexual life in the long run. In addition, the edema of the upper limbs brought about by the axillary lymph node dissection often performed in the past can also affect the comfort of sexual life, making intercourse difficult or even painful. Overall, these problems not only affect normal sexual health, but also the relationship. Even if the partner does not mind the results of the procedure, women may mistakenly think that the partner is devastated and voluntarily give up on the relationship and sex. Therefore it is important to know yourself correctly, your partner may not think that the change in your appearance has any impact, and your own confidence is most important. In addition to surgery, almost all anti-cancer drugs can cause decreased libido. For premenopausal women, chemotherapy may cause premature ovarian failure, causing estrogen deficiency, which manifests as vaginal dryness, premature symptoms, and lack of libido. Because of these physiological changes, painful intercourse, inflammation and bleeding may result. The persistence of uncomfortable symptoms makes women still believe they are in the midst of a disease and thus more reluctant to have sex. Studies showing the effects of endocrine drugs such as tamoxifen on sexual function have been contradictory and inconclusive. For example: the Breast Cancer Prevention Trial found only subtle differences in sexual function between those taking tamoxifen and those not taking it, meaning that there was not much of an effect on sexual function. The effect of aromatase inhibitors such as letrozole and anastrozole on sexual function is not known, and we need more trials to answer these questions. Radiation therapy can cause local changes that affect breast sensitivity, leading to fibrosis, skin thickening, contractures or changes in skin texture and color, sometimes even causing breast pain, any of these abnormalities can have an impact on sexual desire and enjoyment of sexual cancer that will slowly recover over time. Addressing sexual dysfunction requires a multi-connected and sensual approach, preferably with open communication. The key problem is lack of awareness, many times treatment and control of the condition is the sole aim of busy doctors and these issues of libido, fertility and daily follow up are often pushed to gynecologists, nurses and social workers to carry out and people often ignore the issue because it is difficult to talk about it. Estrogen is a key hormone for sexual function, playing a role in stimulating libido, peripheral and pelvic sexual responses. In addition, estrogen affects the genitourinary system, not only by contributing to the maturation and proliferation of epithelial cells, increasing vascular density and blood flow, but also by stimulating glandular secretion. A decrease in estrogen leads to a decrease in vascular engorgement, causing atrophic vaginitis, painful intercourse and a decrease in sexual desire. Although estrogen is very important and its use in breast cancer patients is controversial, it is contraindicated in patients with hormone receptor-positive breast cancer, and recent randomized studies have shown that hormone therapy increases the incidence of breast cancer in patients 3-fold. The use of estrogen is clearly effective in patients with sexual dysfunction leading to severe conjugal disruptions, for whom topical preparations can be used. Topical vaginal preparations are effective in relieving local symptoms and are capable of minimal absorption. The quality of life of a breast cancer patient is very important and those involved in the care of a breast cancer patient, especially the husband, should recognize the manifestations of sexual dysfunction and adjust slowly with your partner, as most difficulties can be resolved over time. Your partner may lose confidence and worry about having any attraction left. You can express your affection physically and mentally. Your partner may not see the change in your appearance as a problem, and you can sit down and discuss it slowly. Even if you don’t feel like having sex, you can show him how much you care by giving him hugs, kisses and massages. You can dim the lights in your underwear and wait until he’s ready, there’s no specific time.