Under normal circumstances, the peptone of food protein decomposition is easily digested and not or rarely absorbed into the blood, but in an excessive amount of food at one time, such as eating a large amount of meat or eating seafood while drinking a lot of alcohol, resulting in the increased permeability of the gastrointestinal mucosa, the peptone can be absorbed into the blood through the intestinal mucosa and lead to the onset of the disease, appearing with red and congested skin, wind mass, with headache and weakness. The duration of the disease is very short, usually lasting only 1-2 days, and most of them can be in 1-4 hours hours. In general, no special treatment is needed, oral antihistamines such as loratadine, etc. The main thing is to control the diet, avoid eating seafood and meat, preferably fasting for half a day to a day, and then gradually resume eating. The disease is not uncommon in children, and there have been reports of children around 2 years old who developed the disease from drinking alcohol.