Coughing at 1:30 a.m. is mainly considered to be caused by inflammatory diseases of the respiratory system, but may also be caused by cough variant asthma. If the patient has a frequent cough with coughing sputum, most of them are caused by chronic bronchitis, which induces coughing at night after sleep because the sputum is not expelled in time, causing it to accumulate in the airways. Dry cough and no sputum need to be considered as caused by cough variant asthma. Cough is also induced when the vagus nerve is more excited during sleep at night, which affects airway dilation and causes bronchospasm. If the patient has a history of heart disease, it also needs to be considered that the cough and sputum occur due to increased cardiac return after sleep resulting in a burden on the heart and causing pulmonary edema.