Patient female, 60 years old, was admitted on 2015-2-16 with the main reason “intermittent chest suffocation, tightness of breath, chest pain aggravated for 20 days with generalized swelling for 4 days”, diagnosis: severe sepsis septic shock multiple organ dysfunction syndrome (type II respiratory failure, heart failure, renal failure liver dysfunction) lung infection (bacterial, fungal) ) diffuse intravascular coagulation bilateral lung secondary tuberculosis smear negative retreatment bilateral pleurisy peritoneal effusion pericardial cavity effusion moderate anemia hypoproteinemia blood electrolyte disorders hypertension coronary artery disease? Allergic dermatitis, the patient was admitted to the hospital with obvious gas tightness, sitting position, heart rate of about 130 times/minute, coughing sputum weakness, poor spirit, a large number of wet bow trekking large treating type II respiratory failure in both lungs can be heard, the condition is critical and life threatening at any time. Director Zhao Aibin rushed to the patient’s side at the first time, actively organized everyone to resuscitate, immediately performed tracheal intubation, there was renal failure, contacted nephrology experts to give emergency peritoneal dialysis, at the same time, the patient had shock, general petechiae and bleeding spots, gave active anti-infection, blood volume replenishment, infusion of coagulation factors, anticoagulation symptomatic treatment, the patient’s condition finally stabilized, given to remove the tracheal intubation, on February 27 On February 27th, the patient again appeared drowsy, did not answer questions, breathing was superficial, and a large amount of humid orifice could be heard in both lungs. During the Spring Festival, most members of our intensive care unit were not able to spend a full year with their families, but in exchange for the patient’s stable condition, we felt that all the efforts and efforts were worthwhile.