The main differences between anal fissure and intestinal cancer are as follows: 1. The causes of anal fissure are different; the formation of anal fissure is mainly related to long-term constipation, while the symptoms of intestinal cancer are mainly caused by cellular deterioration and cancer. 2. The symptoms of anal fissure are different; many small fissures appear on the skin at the end of the rectum, which may cause bleeding, but the color of the blood is bright red and the amount of bleeding is less. The blood color is bright red and the amount of bleeding is small. The location of bowel cancer changes with the appearance of the lesion, and bowel cancer can easily lead to pus and blood, and can also lead to other lesions such as stool deformation and intestinal obstruction. 3. The treatment methods for the two are different. For the treatment of bowel cancer, it needs to be removed by surgery and treated with radiotherapy and chemotherapy, and the prognosis of bowel cancer is relatively poor.