Does infection with Mycobacterium tuberculosis necessarily lead to disease?

  Many people with fear of tuberculosis, in fact, tuberculosis is not so terrible, to get tuberculosis is not easy 1, China’s universal implementation of vaccination, although not completely prevented from getting tuberculosis again, but has raised the threshold, especially the possibility of systemic transmission is almost controlled.  2, tuberculosis is mainly respiratory transmission, only droplets of 5 microns or less have the opportunity to enter the alveoli. Even if it enters, it does not necessarily develop, but also depends on the virulence of the bacteria, whether the body’s immunity is not in the state, poor virulence can not be viable, strong physical strength can kill, and the number of one-time entry, less difficult to start the disease. Studies have shown that only 5% of people who come into contact with tuberculosis will be infected, and only 5% of those infected will develop the disease.