Itching at the base of labia majora is usually caused by pathogenic microbial infections, common causes include bacterial infection, eczema, trichomonas vaginalis, vulvovaginal pseudomonal yeast disease, gonorrhea, condyloma acuminata, etc. 1. bacterial infection: due to daily lack of hygiene, resulting in bacterial infection and symptoms of vulvar itching, it is recommended to keep the vulva clean and hygienic, wash the vulva with water, change underwear regularly and disinfect in the sun. 2, eczema: there can be itching of the labia majora and mossy skin around it. It is recommended to perform routine blood tests and allergen tests to confirm the diagnosis. Local medication or oral medication can be used to treat the condition. Daily control of indoor temperature and humidity, smoking and alcohol cessation, prohibition of strong tea and coffee, etc.; 3. Trichomonas vaginitis: there can be vulvar itching, increased vaginal discharge with burning and painful symptoms, it is recommended to go to the hospital for vaginal discharge examination to confirm the diagnosis and take oral medication under the guidance of a doctor; 4. The diagnosis should be confirmed by examination of vaginal secretions, and antifungal infection drugs can be taken locally or orally; 5, gonorrhea: it can be manifested as itching and burning sensation in vulva, accompanied by purulent vaginal discharge. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. Surgical treatment is also an option.