Children with congenital heart disease are able to have children after surgery to correct their deformities. First of all, heart disease is a disease of the circulatory system, while fertility is a disease of the reproductive system, and it is perfectly possible to have children as long as the reproductive system is healthy and its heart function allows. Secondly, congenital heart disease is a polygenic genetic disease, and it is now recognized that congenital heart disease is caused by genetic factors and environmental factors or both, especially the latter is important. Therefore, the future children born to mothers or fathers with congenital heart disease may not necessarily have the disease. Of course, all people with congenital heart disease hope to have a healthy child when they become parents themselves. The best way to do this is to go to a hospital for premarital testing and genetic counseling before marriage. The parents with congenital heart disease can have a chromosomal examination before marriage to rule out genetic factors, and go to a cardiology hospital to review the cardiac ultrasound and assess whether the heart function is suitable for delivery and which type of delivery method is suitable, and listen to the advice of specialists depending on the type of disease. If a mother who has had valve replacement requires oral anticoagulation, the treatment regimen should be adjusted during pregnancy. Echocardiography in the fetal period can also detect serious congenital heart disease in time for early detection and treatment.