The hybridization method is a clinical treatment that combines modern surgical techniques and interventional techniques. In recent years, it has been increasingly used in the treatment of surgical cardiovascular diseases. In particular, rapid progress has been made in the treatment of complex precardial diseases, with remarkable results. The fundamental reason why hybridization methods have made great progress in recent years is that surgical and interventional techniques have improved qualitatively based on the development of materials, technology and manufacturing techniques; on the other hand, many severe cases require the combined application of multiple clinical tools for simultaneous or sequential treatment in order to ultimately obtain good results, and complex precordial disease is particularly prominent in this regard. (1) Complex precardiac disease often involves the heart, lungs and large blood vessels at the same time, and it is difficult to cover all malformations with a single treatment. (2) Complex precardiac disease often requires staged treatment, and repeated surgical procedures will undoubtedly increase the risk and difficulty of treatment. (3) Children need different treatments at different ages. For these reasons, hybridization methods, especially staged hybridization methods, are well suited for the treatment of complex precardiac disease. The main applications of hybridization techniques in the treatment of complex precardiac disease are as follows: 1. Severe tetralogy of Fallot and pulmonary atresia/ventricular septal defect combined with important body pulmonary side branches or combined with peripheral pulmonary artery stenosis: a. Interventional methods to dilate and support pulmonary artery branch stenosis in parallel with cardiac surgical correction; b. Surgical correction first and postoperative interventional methods to dilate and support residual pulmonary artery stenosis or pulmonary branch stenosis; c, major body pulmonary side branch embolization or temporary embolization see surgical correction 2, surgical open-heart-interventional sealing of apical ventricular septal defect in small infants 3, hybrid treatment of combined cardiac and macrovascular lesions: surgical procedure for cardiac malformations – interventional treatment of vascular malformations 4, hybrid treatment of simple complete transposition of the great arteries: postnatal acute balloon atrial septal dilation and then elective surgical radical surgery 5, left heart dysplasia syndrome: instead of Norwood surgery, reduce the surgical risk 6, hybrid treatment of single ventricle: reduce the number of staged palliative surgery 7, surgical treatment of the original residual lesion of the follow-up intervention to reduce the difficulties and risks of reoperation. For example: interventional reimplantation of bioprosthetic valve of extra-pulmonary artery duct; interventional sealing of body-pulmonary bypass artificial vessel; interventional treatment of residual aortic constriction or recurrence of aortic constriction after surgery. 8, hybridization of congenital arrhythmias In conclusion, hybridization methods are increasingly used for those complex precordial diseases for which satisfactory results cannot be obtained by simple surgical or interventional treatment or one-stage surgery. Due to the application of this technology, the indications for the treatment of complex congenital heart disease have been expanded and the potential risks associated with multiple surgical procedures have been effectively reduced, thus achieving initial good clinical results.