Indications: Patients with clinical stage I and II, masses less than 3 cm maximum diameter masses greater than 3 cm or stage III, after preoperative chemotherapy downstaging – consider with caution. Mass to breast volume ratio – breast with appropriate volume and ability to maintain cosmetic results after surgery Absolute contraindications: Multicentric lesions in two or more quadrants in those who cannot receive radiotherapy cannot be guaranteed negative pathological margins Relative contraindications: Tumor located in the central region of the breast (areola and parametrium 2cm), including nipple Paget Local treatment for breast-conserving treatment: excision of the primary site should include the tumor, 1-2 cm of tissue surrounding the tumor, and axillary lymph node dissection of the deep pectoralis major muscle fascia, or whole-breast radiotherapy with biopsy of the anterior lymph nodes. The systemic treatment of lymph node dissection surgery.